Alzheimer's breakthrough: 2 hrs of sleep restored without clearing brain plaques

(sciencedaily.com)

40 points by amichail2 hours ago

2 comments

unification_fan1 hour ago
From what I know about terminal lucidity in alzheimer's patients it seems to me that these plaques act like electrical resistors that increase the impedance for neurotransmission. But chemically of course. So if you push more current through the system, such as when you're dying, you can suddenly access memories that were locked off. Is my understanding correct?
- yrjrjjrjjtjjr1 minute ago
 Even prior to this study I've seen people post memes about terminal lucidity. In subsequent discussion people have said it's related to the immune system finally giving up, reducing inflammation, leading to increased perceived health. And then you die from what the immune system was keeping at bay.So this study ties in neatly with that.
- lithos2 minutes ago
 One of the fraud filled paths in science.More like rust, where once it starts it allows the process to speed up. In this case collecting poisons.
rsyring2 hours ago
...in mice.Not knocking the research, cure it already! I just think it should be in the title to avoid false hope.
- gdulli38 minutes ago
 We're adults like you are and can manage both our emotions and the responsibility of understanding that headlines aren't the totality of information.
 - ShinyLeftPad34 minutes ago
 When it is taking about a breakthrough in treatment of a human disease, it's kind of important if it's not actually in humansAlso "headlines aren't the totality of information" doesn't mean there's no clickbait headlines...
 - Brian_K_White26 minutes ago
 It's utterly unimportant. It's all research and all progress and all works towards our benefit eventually. The fact that an important discovery is still in the mouse stage and not yet in the human stage doesn't make it any less important or interesting, unless you are unutterably simple.Put another way: the "in mice" doesn't matter because they are studying alzheimers, not mice. the mice are just the lab equipment of the moment. I don't care what kind of glassware or computers they use either.
 - dolorian0 minutes ago
 It depends on what's being studied. There are mice studies on diet which obviously don't carry over to human beings since we don't have similar digestive systems. It may be true (arguable) that all research data is of some benefit, but don't expect people to be as excited about mouse research as human research.How do they get the alzheimers mice? Article doesn't say. Usually in studies they take healthy mice and induce the condition artificially. That can be a confounding factor since the condition isn't induced in the specimens we care about (human beings). Is it even the same condition?
- s1artibartfast34 minutes ago
 No, you cure it already!